Weekend Research Reads #4

This week's readings have been all over the place.

1. Zinc oxide nanoparticles provide anti-cholera activity by disrupting the interaction of cholera toxin with the human GM1 receptor (Link)
2. Association between Childhood Diarrhoeal Incidence and Climatic Factors in Urban and Rural Settings in the Health District of Mbour, Senegal (Link)
3. Comparison of two control groups for estimation of oral cholera vaccine effectiveness using a case-control study design (Link)
4. Passive, health center-based assessment of adverse events following oral cholera immunization in Nampula city, Mozambique (Link)
5. Enteric Infections Circulating during Hajj Seasons, 2011-2013 (Link)
6. Economic Assessment of Waterborne Outbreak of Cryptosporidiosis (Link)

A splendid example of Kandinsky's biomorphic art, Colorful Ensemble, this month's cover art, shows that regardless of this shift in approach, the artist's lifelong passion for infusing his art with musical themes and imagery continued to be at the heart of his work. What at first viewing appears to be frenzied, haphazard chaos yields to a pervading sense of harmony. The neutral background issues a tranquil invitation to peer more carefully at the mass of teeming shapes and bold primary colors enclosed by the heart-shaped figure.

Kandinsky studs the blue border with small bejeweled images, miniature constellations of color and harmony that may be separating from the whole or moving toward absorption. Densely packed scores of perfect circles create a textured mosaic. Curious interspersed forms evoke musical imagery: the head of a guitar, a stringed harp, and breath marks. Other shapes within the painting resemble biologic structures, including flagella, ribosomes, and genetic material found in bacteria.

Kandinsky created his biomorphic art during a time of crucial discovery and innovation in treating bacterial infections. The physicist Ladislaus Laszlo Marton had recently examined biologic specimens with an electron microscope and published the first electron micrographs of bacteria. Alexander Fleming had discovered penicillin just a decade earlier, and antibiotics were for the first time being widely used to treat bacterial infections.

1. Transmission of antibiotic resistance from pigs to humans: trues and lies (Link)
2. Escherichia coli resistance and gut microbiota profile in pigs raised with different antimicrobial administration in feed (Link)
3. Impact of "Raised Without Antibiotics" Beef Cattle Production Practices On Occurrences of Antimicrobial Resistance (Link)
4. Clinician-targeted interventions to influence antibiotic prescribing behaviour for acute respiratory infections in primary care: an overview of systematic reviews. (Link)
5. Evolution of antibiotic resistance without antibiotic exposure (Link)
6. Antimicrobial resistance gene acquisition and depletion following fecal microbiota transplantation (FMT) for recurrent Clostridium difficile infection (Link)
7. Antimicrobial Drug Prescription and Neisseria gonorrhoeae Susceptibility, United States, 2005-2013 (Link)
8. Off-Label Use of Bedaquiline in Children and Adolescents with Multidrug-Resistant Tuberculosis (Link)
9. Bedaquiline and Delamanid Combination Treatment of 5 Patients with Pulmonary Extensively Drug-Resistant Tuberculosis (Link)
10. Six-Month Response to Delamanid Treatment in MDR TB Patients (Link)

A system dynamics approach to understanding the One Health concept. (Link)

"One Health Cosmos".One Health Cosmos shows the relationships between the various disciplines and complex problem descriptors that are reported to fall within the One Health concept. Squares and circles represent nodes, and the arrows connecting nodes represent causal links. Brown color is used to show positive causal link which also have a "+" sign besides the arrowhead. Negative causal link is portrayed with a blue color and "-" sign besides the arrowhead. A positive causal link means that both the causative and the resultant factors increase or decrease in the same direction. A negative causal link indicates that the two linked factors change in opposite directions. The positive reinforcing loop has a "R" in the clockwise cycle. A negative reinforcing loop opposite has a "B" in the counterclockwise cycle. A big arrow shows the direction of this relationship between disease and health through One Health.

1. People, Patches, and Parasites: The Case of Trypanosomiasis in Zimbabwe (Link)
2. A Controlled Trial to Reduce the Risk of Human Nipah Virus Exposure in Bangladesh (Link)
3. Monitoring Avian Influenza Viruses from Chicken Carcasses Sold at Markets, China, 2016 (Link)

Impact of climate change on vector transmission of Trypanosoma cruzi (Chagas, 1909) in North America (Link)