Brsm

LATEST ARTICLES ( 57 )

• (+/-)-Harringtonolide

  

  Stereoselective Total Synthesis of Hainanolidol and Harringtonolide via Oxidopyrylium-Based [5 + 2] CycloadditionWeiping Tang et al., J. Am. Chem. Soc., 2013,... Read more

  Posted on 23 August 2013 SCIENCE, TECH

• US Here I Come!

  Hi all, Somewhat later than planned, I'm off to the US tomorrow to finally start my postdoc! I suspect I'm gonna be pretty busy finding a place to live and... Read more

  Posted on 24 July 2013 SCIENCE, TECH

• Woodward Wednesday 7: Steroids

  

  R. B. Woodward et al., J. Am. Chem. Soc., 1952, 74, 4223 [PDF] (Full paper)For preliminary communications see: JACS, 1951, 73, 3547 [PDF]; JACS, 1951, 73, 3548... Read more

  Posted on 16 July 2013 SCIENCE, TECH

• Non-Thermal Microwave Effects: Probably Still Bollocks

  

  Thanks to Brandon and Martyn for pointing out these publications. Be warned, this post turned out seriously long and wordy!Almost since the dawn of microwave... Read more

  Posted on 05 July 2013 SCIENCE, TECH

• And Now For Something Completely Different 8: Summarising Blogs With Wordle

  

  Reading blogs is fun, but find new ones that you'll enjoy can be time consuming. Fortunately, there's a really useful tool to simplify the process: Wordle. Read more

  Posted on 18 June 2013 TECH

• (-)-Nakadomarin A

  

  Total Synthesis of (–)-Nakadomarin ADavid A. Evans et. al., J. Am. Chem. Soc., 2013, Just Accepted [PDF] [SI] [GROUP]DOI: 10.1021/ja404673sAt first glance I... Read more

  Posted on 16 June 2013 SCIENCE, TECH

• Pentacycloanammoxic Acid

  

  Today's guest post is from Siddharth Yadav, an enthusiastic young chemist from somewhere in India. Enjoy! I found B.R.S.M. when I was searching the web for the... Read more

  Posted on 13 June 2013 SCIENCE, TECH

• (-)-Neothiobinupharidine

  

  I've not written all that many total synthesis posts this year, not for a dearth of interesting work, but more a lack of free time. I started writing this one... Read more

  Posted on 12 June 2013 SCIENCE, TECH

• BRSM is Two Years Old Today!

  

  I had completely forgotten that today was my 2nd anniversary as a blogger until my girlfriend sent me this photo a bit earlier:Apparently, as there were no... Read more

  Posted on 10 June 2013 SCIENCE, TECH

• And Now For Something Completely Different 8: XKCD-style Venn Diagrams

  

  Thanks to a recent xkcd comic I've just discovered a wonderfully concise new way to communicate – non-overlapping Venn Diagrams:  From http://xkcd. Read more

  Posted on 02 April 2013 SCIENCE, TECH

• And Now For Something Completely Different 7: Green Chemistry

  

  Most of the credit for this one goes to occasional commenter Martyn!Is it just me, or will green chemistry journals publish anything these days? Read more

  Posted on 01 April 2013 SCIENCE, TECH

• Woodward Wednesday 6: Reserpine (Part 2/2)

  

  Okay, this second post is a lot later and a fair bit shorter than I had hoped it would be, but it's been a crazy and not entirely pleasant month. Enjoy! Read more

  Posted on 27 March 2013 SCIENCE, TECH

• And Now For Something Completely Different 5: The Merck Index Challenge

  

  Sorry things have been so quiet around here; it's been a hectic month! Here's something silly born of an unusual conversation over coffee. The office... Read more

  Posted on 26 March 2013 SCIENCE

• Guest Post: Pactamycin (Hanessian, 2012)

  

  To mix things up a bit, I've traded posts with Brandon from Chemtips, who's going to be telling you a bit more about Hanessian's pactamycin work in this... Read more

  Posted on 04 March 2013 SCIENCE, TECH

• Woodward Wednesdays 6: Reserpine (Part 1/2)

  

  I'm going to do this one in two parts, in the hope that posting the first half now will force me to find time to write the second part at the weekend. Also,... Read more

  Posted on 20 February 2013 SCIENCE, TECH

• From Pasta to Superconductor In Four Easy Steps

  

  From Chem. Commun., 2013, ASAP (DOI: 10.1039/C3CC38271K)Seriously. From the abstract:"Self-supporting superconducting replicas of pasta shapes are reported,... Read more

  Posted on 07 February 2013 SCIENCE, TECH

• Oh, Sigma…

  

  I'm a little busy with blog-syn and actual work at the moment, but a friend just sent me this screenshot from the Aldrich website, which I think I'll share... Read more

  Posted on 06 February 2013 SCIENCE, TECH

• Guest Post: 50p

  

  As some of you might remember, towards the end of last year DrFreddy over at Synthetic Remarks offered out his services as a guest blogger to anyone... Read more

  Posted on 29 January 2013 SCIENCE, TECH

• (+)-Hyperforin (Shair, 2012)

  

  Okay, I've finally got round to a full post on this synthesis. I started writing this almost two weeks ago! More things soon. Enjoy! Enantioselective Total... Read more

  Posted on 20 January 2013 SCIENCE, TECH

• Who Ya Gonna Call? Blog Syn!

  Ever see a reaction in the literature and think, "that seems a little too good to be true..."? Retro Baeyer-Villiger reaction? Quantitative cleavage of methyl... Read more

  Posted on 16 January 2013 SCIENCE, TECH