Except from the two things we can be sure of in life: death and taxes, there is a 3rd most folks can count on, arthritis. It affects nearly 70% - 80% of the population over the age of fifty. The most common kind is named: osteoarthritis or degenerative arthritis, which is an inflammatory disease. Symptoms are: early morning stiffness, swollen joints and joint pain over the complete body. In an advanced state, it will cause significant pain, discomfort and even disability. Osteoarthritis is caused by degeneration of the cartilage in the joints or the lining of the joints. The cartilage can wear out utterly by stress, caused by too much weight, trauma or activity.
Current cartilage breaks down, while new cartilage is formed. This method must be kept in balance in order to keep healthy joints. There are many causes of swelling in our joints. The cytokins are among the leading causes. These are proteins that carry messages between cells and regulate immunity and inflammation. The second cluster is the proteases, enzymes that cause the breakdown of proteins. The third group are the phagocytes (or neutrophils), that are attracted to the inflamed joint whereas trying to clear this reaction and to prevent damage to the cartilage and lining of the joint.
Joint Swelling
However this inflammatory response can truly cause a large amount of swelling to the joint. The strain caused by our weight on our joints block the blood going to the cartilage. This phenomenon is named Ischemia. Once we take weight off the joint, the pressure is reduced and blood returns back to the cartilage, this is often known as reperfusion. This method causes excessive production of free radicals. These free radicals put serious weight on the antioxidant defense system and cause oxidative stress and consequently harm to the cartilage and synovial lining of the joint.
Rheumatoid arthritis
Rheumatoid arthritis is another form of arthritis. This is often an autoimmune disease. When our immune system starts to attack the cartilage and additionally the synovial lining of the joint, an inflammatory process starts to destroy healthy tissue. This not only creates extreme free radicals, however conjointly attracts TNF-a cytokines. Creation of free radicals is five times higher in patients with rheumatoid arthritis than in patients with osteoarthritis and causes larger oxidative stress and harm to the joints. This damaging impact will cause harsh pain and deformity.
Traditional treatments
When considering traditional treatments, it's important to grasp the important causes of these diseases. The older form of treatment of both sorts of arthritis, referred to as nonsteroidal anti-inflammatories (NSAIDS) and aspirin, caused acute side effects, like abdomen ulcers and higher -gastrointestinal bleeding (GI). As a result of this, pharmaceutical corporations developed a group of new NSAIDS, called COX a combination of inhibitors, which significantly reduced GI. Sadly, these have side effects as well, like bowel perforation and higher GI bleeding. These medications mainly cut back the pain however does nothing about the basic reason for the disease, which is oxidative stress.
Antioxidant supplement
Using a well balanced, high quality mineral and antioxidant supplement, patients with severe arthritis should conjointly take glucosamine sulfate, which is one of the fundamental nutrients for the synthesis of cartilage. It is an easy amino sugar and provides the cartilage its elasticity. Not like NSAIDS and aspirin, that solely reduce the pain, glucosamine helps to rebuild the damaged cartilage.
Chondrotin sulfate is often combined with glucosamine so as to make the cartilage more pliable and spongy, as chondrotin attracts water into the cartilage. Without it, the cartilage becomes drier and much more fragile. Cellular nutrition is the key to stop arthritis. This is often another area that nutritional supplements work along together with your body to help insure regaining your health.
