If you want to pick up Manila ladyboys, the best place to head to would probably be a place in the Malate district called Exklusiv Nightclub. For many years, it has been a known hot spot where you can meet ladyboys. Locals will tell you it is the first place to go if you want to meet Manila ladyboys who aren't "in the business".
Apart from this place, you could go to some LGBT friendly clubs and bars like Nectar Nightclub in Taguig or Club Mankind in Quezon City. These are more like gay clubs, but there are TS there now and then. There are lots of places where you can take ladyboys - TS friendly hotels abound in the capital.
The biggest bar in Manila is near the main mall in the Makati district. A lot of ladyboys will be working there as well. It is probably less than 5% trans, but locals say there are always at least several TS there after 10 pm every night.
You can also pick up Manila ladyboys at one of several go-go bars near the beach. The best-known ones are the Siren Bar, Mikko's Bar, and Hiya's Bar. All three places offer shows from 7.30 to 8.30 pm and from 9 to 10 pm on Fridays and weekends (exceptions in low season or adverse weather conditions). The crowds there enjoy one of a kind drag, TS, and TV shows. There's great music at the beach that you can dance to. The shows always attract TS so the odds of meeting one are higher at this time.
There is a ladybar bar in the Makati District called Mixed Nuts. It has the best ladyboys and shemales in Manila and is open daily between 10 pm and 4 am. Mixed Nuts has an entertaining show starting around midnight every night.
