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About Half of Chronic Pain Research Remains Unreported

Posted on the 27 May 2014 by Soumyadeepb
Results from more than half of clinical trials for common chronic pain disorders are not readily available on global registries, according to a new paper in the journal PAIN [1]. The survey included 15 major registries accessible through the World Health Organisation’s International Clinical Trials Registry Platform. Of the 447 unique trials identified, only 46% had results available. Dr Michael Rowbotham, Scientific Director of the California Pacific Medical Center Research Institute and lead study author:

Many patients enter clinical trials with the belief that by taking part in research, they will help other patients in the future. For that to happen, the results of this research must be transparent and fully available.

AllTrials co-founder Dr Ben Goldacre:

Once again we see that half of all trial results for currently used treatments are missing. While industry groups like the ABPI give false reassurance, and try to pretend that this problem has gone away, patients are being unnecessarily harmed. Industry, regulators, patient groups, professional bodies and the research community need to take action, show leadership, and address this problem urgently.

Capture The same is true for research on all domains. It’s time all clinical trial results are reported. Patients, researchers, pharmacists, doctors and regulators everywhere will benefit from publication of clinical trial results. Wherever you are in the world please sign the petition: Thousands of clinical trials have not reported their results; some have not even been registered. Information on what was done and what was found in these trials could be lost forever to doctors and researchers, leading to bad treatment decisions, missed opportunities for good medicine, and trials being repeated.   All trials past and present should be registered, and the full methods and the results reported. Join the AllTrials Campaing to call on governments, regulators and research bodies to implement measures to achieve this by signing the petition here.

[1] “RReACT Goes Global: Perils andPitfalls of Constructing a Global Open-Access Database of Registered Analgesic Clinical Trials and Trial Results,” by Troels Munch; Faustine L. Dufka; Kaitlin Greene; Shannon M. Smith; Robert H. Dworkin; Michael C. Rowbotham (DOI: http://dx.doi.org/10.1016/j.pain.2014.04.007). It appears online ahead of PAIN®, Volume 155, Issue 8 (August 2014) published by Elsevier.

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