Abstract
Adrenoleukodystrophy is a genetic disorder that affects the nervous system and adrenal glands. This genetic disease is more common in boys and they show symptoms in the early age group of 4 to 10 years. The symptoms and progression can worsen with time which can also lead to total disability in the child. Life expectancy depends on early diagnosis and proper treatment. The condition and life expectancy can vary according to the type and duration of the treatment. In this article, we will discuss all the symptoms and causes of Adrenoleukodystrophy, along with its management in Ayurveda without the additional side effects.
Introduction
Adrenoleukodystrophy is a genetic condition that damages the myelin sheath (membrane around the brain and the spinal cord). It is an X-linked disorder that reduces the ability of the nerves to transmit information to the brain. The electric impulses go slow when the myelin sheath is damaged. Adrenoleukodystrophy is characterized into flowing four types-
- Childhood Cerebral ALD
- Adrenomyeloneuropathy
- Addison's Disease
- Asymptomatic
The signs and symptoms for each type appear between early childhood and middle age. The symptoms are common and tend to worsen with time if not treated properly. Severe cases of Adrenoleukodystrophy may develop Cerebral x-linked Adrenoleukodystrophy. Some children may not show clear symptoms but the medical tests show biochemical abnormalities. These types of Adrenoleukodystrophy can also be seen in the same genetic family.
Ayurvedic Aspect
In Ayurveda, the genetic disorders are directly laid as Beej Dushti or Beej Pradoshaj Vikaras. The body energies Vata, Pita, and Kapha are responsible for these types of abnormalities. Improper and unhealthy dietary and lifestyle habits can lead to genetic abnormalities. Poorva Karmas are also said to be responsible for these genetic variations in Ayurveda. Thus medicinal and spiritual therapy both are practiced hand in hand for the proper treatment of Adrenoleukodystrophy.
Causes
Adrenoleukodystrophy is caused due to-
- Mutations and variations in gene ABCD1
- ABCD1 gene instructs for the proper production of Adrenoleukodystrophy (ALDP) Protein. The mutation in this gene minimizes the production of ALDP.
- This also leads to the destruction of myelin sheaths in the brain and spinal cord.
Symptoms
Symptoms of Adrenoleukodystrophy due to the destruction of the myelin sheath and low production of ALDP could be -
- Loss of vision
- Deafness
- Seizures
- Learning disabilities
- Difficulty in balancing
- Nausea
- Vomiting
- Fatigue
- Weight loss
- Adrenocortical insufficiency
- Aggressive behavior
- Urinary problems
- Stiffness
- Weakness in legs
- Difficulty in swallowing
- Poor coordination
- Coma
Diagnosis
The diagnosis is made by observing the physical symptoms and watching the family history. Diagnostic tests done are
- Blood tests
- Fibroblast cell culture
- MRI scan
- Vision screening
- Skin biopsy
Treatment
There is no cure for Adrenoleukodystrophy in modern medicine. Yet, many medications are used to manage the symptoms
- Drugs to reduce stiffness
- Anti-seizure drugs
- Physical therapy
- Adrenal insufficiency treatment
- Gene therapy
- Stem cell transplant
Ayurvedic Treatment
Ayurvedic treatment can be very effective in managing Adrenoleukodystrophy. Various herbal modalities help to manage such genetic diseases naturally. Planet Ayurveda company offers pure medicines for the management of various disorders throughout the entire world. Treatment includes long-term medications along with modalities offered by the company. The treatment done by our doctors is completely ayurvedic and the medicines prepared by us are pure and potent enough to ease the symptoms. All medicines from tablets to capsules, even syrups are made from 100% pure natural standard extracts of the herbs, without any adulteration and chemicals. Planet Ayurveda offers treatment for Adrenoleukodystrophy with the following listed potential herbal formulations-
- ASHWAGANDHA CAPSULES
- BRAHMI CAPSULES
- GOTU KOLA CAPSULES
- RASRAJ RAJ
- GILOY CAPSULES
- SPIRULINA CAPSULES
PRODUCT DESCRIPTION
1. Ashwagandha Capsules
These capsules are manufactured from the herbal extracts of the herb Ashwagandha ( Withania somnifera). This herb increases body strength by enhancing immunity to fight against infections. Ashwagandha has very potent results as a medicinal herb that also has remarkable results in several disorders as it balances Vata, Pitta, and Kapha doshas. It effectively cures many body ailments and manages various diseases effectively, one among them is Adrenoleukodystrophy.
Dosage - Take 1 capsule twice a day
2. Brahmi Capsules
Standard extracts of the coolant herb Brahmi ( Bacopa monnieri) are used to manufacture these capsules. Brahmi has been used since ancient times for managing various mental disorders. Brahmi is considered as Roga-Nashini ( eliminate mind ailments), Deergh-aayu and has also proved its effectiveness in Adrenoleukodystrophy.
Dosage - Take 1 capsule two times a day with water.
3. Gotu Kola Capsules
These herbal capsules are manufactured from pure extracts of Mandookparni ( Centella asiatica). These capsules will help to maintain psychic energies in balance. These mind energies are Satva, Rajas, and Tamas which keep the mind healthy. These capsules will overcome the symptoms produced due to the destruction of myelin sheath I Adrenoleukodystrophy.
Dosage- Take 2 capsules twice daily.
4. Rasraj Ras
This is a classical formulation to keep the Vata dosha balanced. It contains Ras sindoor (Processed mercury), Loha Bhasma ( Iron calx), Vanga bhasma ( Tin calx), Lavang ( Syzygium aromatic), kakmachi ras ( Solanum nigrum), etc. This medicine is basically instructed for the treatment of neuromuscular disorders such as hemiplegia, locked jaw, dizziness, and strengthening the body by overcoming weakness and fatigue.
Dosage - Have 1 tablet twice daily.
5. Giloy Capsules
The capsules are made from extracts of herb Giloy ( Tinospora cordifolia). Giloy is used as an immunomodulator that refreshes the inflamed membranes in the body. It also fights against many infections in the body by developing immunity. There is no adverse effect of these capsules and very effectively eases the symptoms of Adrenoleukodystrophy.
Dosage - Have 1 capsule twice daily with water.
6. Spirulina Capsules
These nutritious capsules are prepared from 100% pure extracts of Spirulina. These capsules have many health benefits on immunity, brain, eyes, hemoglobin, body energy, kidneys, heart, allergic reactions, etc. These capsules are very helpful in patients suffering from Adrenoleukodystrophy.
Dosage- Take 1 capsule twice daily.
CONTACT PLANET AYURVEDA TO PROVIDE YOU THE COSTING / ORDERING AND DELIVERY INFORMATION AT - [email protected] OR CALL AT +91-172-5214040Conclusion
Ayurvedic is very effective in managing genetic disorders through various therapies including medicinal, yogic, and spiritual therapies. They are safe to use and have long term side effects, unlike modern medicines. For Ayurvedic experience, consult our ayurvedic doctors at www.PlanetAyurveda.com