A valuable trove of open source articles is provided in the Special Feature section of the Dec. 5 issue of PNAS with an introductory article by Akil and Nestler with the title of this post. The special feature:
...explores the consequences of the broad-scale increase in psychological stress and the evidence that we are facing a second pandemic of depression, anxiety, and other stress-related disorders. The authors of this feature describe challenges faced and scientific advances being made, spanning animal models to human translation, to illustrate new tools and techniques currently being deployed in understanding the biology of stress and resilience and the interplay between genetic and environmental variables.