Brsm

LATEST ARTICLES ( 57 )

• Barium(ii) Iodide – The Shair Method

  

  Full post on this synthesis to come when I get back from holiday at the weekend and can use ChemDraw! Sorry for the hand-drawn stuctures - I've still not found ... Read more

  Posted on 03 January 2013 SCIENCE, TECH

• Synthetic Biology Versus Total Synthesis

  

  From a series of paintings by David Cordes at Pacific University, Oregon. I think most would agree that synthetic chemists can now make just about any... Read more

  Posted on 24 December 2012 SCIENCE, TECH

• What’s Wrong With This Picture 2: An Intriguing Biosynthetic Proposal

  

  As a synthetic chemist I'm always on the hunt for interesting molecules to disconnect/speculate about, and a couple of  natural products published at the start... Read more

  Posted on 16 December 2012 CHEMISTRY, SCIENCE, TECH

• Resource Page and Blogroll: 2012 Update

  I've got a few emails lately pointing me in the direction of good resources such as the much discussed How To Chemdraw video and the beautiful new... Read more

  Posted on 15 December 2012 SCIENCE, TECH

• Non-Thermal Microwave Effects: Probably Bollocks

  

  For a related post on things to check before publishing your controversial results to avoid potential humiliation, see my old piece on 'metal-free' reactions. Read more

  Posted on 15 December 2012 SCIENCE, TECH

• Mulvember 3: Lycoflexine

  

  I'd originally planned to do four of these posts, but it looks like I've run out of time so I'll be getting back to more cutting edge work (as soon as... Read more

  Posted on 02 December 2012 SCIENCE

• Superlatives 3: The Longest Polyene

  

  Update 02-12-12: If anyone wants/needs a copy of the original image without the text and arrow added, you can find it here. Some of you may remember this... Read more

  Posted on 01 December 2012 SCIENCE, TECH

• Mulvember 2: Echinopines A and B

  

  Although there have been a couple of interesting syntheses this week, I'm still very busy so I'm going to write about another Mulzer synthesis from my talk.... Read more

  Posted on 18 November 2012 SCIENCE

• Mulvember 1: Introduction and Penifulvin A

  

  Like many research groups, the one I’m in does weekly literature talks so people get a bit of practice with powerpoint and public speaking. Read more

  Posted on 05 November 2012 SCIENCE

• Chem Coach Carnival: I’m A Postdoc and I Love It

  Hi all, we* interrupt our* scheduled** programming to bring you an exciting** Chemistry Carnival entry! See Arr Oh recently had the brilliant idea of a Chem... Read more

  Posted on 24 October 2012 SCIENCE

• Drugs I Shan’t Be Taking This Week 1: 2,4-Dinitrophenol

  I was saddened and surprised today to read this story on the BBC News website about a young man who died by overdosing on 2,4-dinitrophenol. Huh? Read more

  Posted on 21 October 2012 SCIENCE

• I’ll See Your Diels-Alder and Raise You One 1,3-dipolar Cycloaddition

  

  On Monday, See Arr Oh over at Just Like Cooking posted on this non-obvious Diels-Alder reaction recently published by the Vanderwal group, suggesting that it'd... Read more

  Posted on 20 October 2012 SCIENCE

• Woodward Wednesday 5: t-Butyllithium?!

  

  Although it's been a while I do intend to do at least one full size Woodward Wednesday post this month. In the mean time here's a short (but important) synthesi... Read more

  Posted on 10 October 2012 SCIENCE

• An Uncommon Lab Reference

  

  Last Monday I set my MSci student the task of preparing the above compound and sent him off to do some literature searching. He quickly found a mention of it... Read more

  Posted on 09 October 2012 SCIENCE

• Superlatives 2: The Gassiest Reaction of Them All?

  

  Perhaps Organic and Biomolecular Chemistry isn't a journal well known for its reviews, however I recently enjoyed reading this rather unusual perspective by... Read more

  Posted on 30 September 2012 SCIENCE

• Superlatives 1: The Heaviest Catalyst Ever?

  

  While browsing through the Advanced Synthesis and Catalysis Early View today, I noticed this paper on a new Rhodium catalyst for the asymmetric conjugate... Read more

  Posted on 25 September 2012 SCIENCE

• Alkaloid (-)-205B

  

  Synthesis of Alkaloid (−)-205B via Stereoselective Reductive Cross-Coupling and Intramolecular [3 + 2] Cycloaddition Micalizio et al., J. Am. Chem. Soc., 2012,... Read more

  Posted on 16 September 2012 SCIENCE