Bkoffman
MY BLOGS
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BRIAN KOFFMAN'S AWESOME TRANSPLANT AND CLL ADVENTURE: LEARNING FROM AND ABOUT CANCER
http://bkoffman.blogspot.com/
I HAVE A NEED TO LAUGH, AN UNWILLINGNESS TO ACCEPT THE IMPOSSIBLE, AND A NASTY LEUKEMIA (CLL). BY HAVING A TRANSPLANT EARLY, I WAS HOPING TO SAY "I USED TO HAVE LEUKEMIA" LOOKS LIKE I AM STILL HOPING, THIS TIME IN A CLINICAL TRIAL. BUT THE TELLING OF THE JOURNEY HAS BECOME A JOURNEY ITSELF FOR THIS DOCTOR TURNED PATIENT. I AM DOING MORE TEACHING ON CLL IN PARTICULAR AND OTHER CANCERS IN GENERAL. AFTER ALL, WE ARE ALL IN THIS TOGETHER. EMAIL ME AT [email protected]
LATEST ARTICLES ( 357 )
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Acalabrutinib Phase III ASCEND Trial Met Primary Endpoint at Interim Analysis...
This trial in previously treated CLL patients showed a clinically significant progression free survival when compared to a combination regimen of rituximab... Read more
Posted on 12 May 2019 COMMUNITY, HEALTH -
One Year CAR-T Anniversary to Treat My CLL and an Interview with Dr. Siddiqi...
HiMarch 22, 2019 was my one year anniversary of receiving my experimental CAR-T cells in Seattle.About a month earlier, I got the great news that I remain U-MRD... Read more
Posted on 27 March 2019 COMMUNITY, HEALTH -
CMS Approval of CAR-T Therapy
CMS approves CAR-T therapy payment, but with significant strings attached. For more details see:... Read more
Posted on 17 February 2019 COMMUNITY, HEALTH -
The Evolving Role of Clinical Trials in CLL (chronic Lymphocytic Leukemia)
Hi,As many of you know, I am alive today because of my entering two phase I clinical trials, one for PCI-32765 that later became known as ibrutinib and another... Read more
Posted on 30 January 2019 COMMUNITY, HEALTH -
Upcoming Free CLL Specific Educational Forums for Patients and Caregivers...
We will be holding a total of a dozen free CLL specific ½ day Educational Forums for patients and caregivers across the country over the next few months. Read more
Posted on 23 January 2019 COMMUNITY, HEALTH -
Reflections on Year of Both Great Progress and Great Sadness in the CLL World
Happy New Year.This year we lost 3 members of our local Orange County CLL Society support group, and I lost other 3 other dear CLL and CAR-T friends that I met... Read more
Posted on 29 December 2018 COMMUNITY, HEALTH -
Closing One Door, Opening Another.
December 10, 2018 was a monumental day for me. A huge transition.After 38 years of caring for generations of patients as their family doctor, I retired today... Read more
Posted on 13 December 2018 COMMUNITY, HEALTH -
Off to ASH 2018
Swamped so this will be quick, but I haven't forgotten the blog.I am off to ASH 2018 where we are busy from 7 AM to 10 PM most days. Read more
Posted on 29 November 2018 COMMUNITY, HEALTH -
ASH 2017: Dr. Thomas Kipps on the ROR1 Antibody, Cirmtuzumab
At ASH 2017 held in December in Atlanta, Dr. Thomas Kipps from the Moore Cancer Center at UCSD in San Diego, CA talked about an exciting new target for very... Read more
Posted on 19 August 2018 COMMUNITY, HEALTH -
ASH 2017: Dr. Adrian Wiestner on Resistance Mechanism in CLL (chronic Lymphocyti...
I had the opportunity to interview Dr. Adrian Wiestner from the National Institutes of Health at ASH 2017 in Atlanta GA about his and other researchers work on... Read more
Posted on 11 August 2018 COMMUNITY, HEALTH -
He Did It
Hi,Stan Kurtz and his team, with help from so many of you, Did it. He swam the Catalina channel and raised his goal of over $25.000 for the CLL Society! Thanks... Read more
Posted on 06 August 2018 COMMUNITY, HEALTH -
10 Years Ago Today I Received My Transplant for My CLL (chronic Lymphocytic...
July 1, 2008, Canada Day, was my first Day Zero- my first shot at a cure when after conditioning chemo-immunotherapy of FCR, I received my hematopoietic stem... Read more
Posted on 02 July 2018 COMMUNITY, HEALTH -
I've Go to Admit It's Getting Better: More Good News About My CLL (chronic...
Most of my blog posts can be followed here.The full story of my CAR-T therapy, the incredible rollercoaster and the amazing results can be found there I have... Read more
Posted on 22 May 2018 COMMUNITY, HEALTH -
Get My Car-t Cells Tomorrow for Mycll
Patty and I have been enjoying Seattle. We’ve been here for 3 weeks prepping for the JCAR14 trial at SCCA/Hutch. Tomorrow is my big day- I get the CAR-T cells. Read more
Posted on 22 March 2018 COMMUNITY, HEALTH -
Goldilocks and the CAR-T Cells
I had planned to write more often, but long hospital days, followed by long naps and long walks most days have precluded me doing much more than remembering my... Read more
Posted on 18 March 2018 COMMUNITY, HEALTH -
3/6/2018 Brian's Apheresis at SCCA for CAR-Ts to Treat CLL
Patty reporting from Seattle Cancer Care Alliance March 6, 2018: Apheresis! Using a sophisticated centrifuge, Brian’s T-cells are being spun off and will be... Read more
Posted on 06 March 2018 COMMUNITY, HEALTH -
Me and My CAR-T- Part 1 on Why I Have Moved to Seattle for 2 Months to Treat My...
First things first.Thank you.I have been overwhelmed by the support and prayers I have received in the past few days by email, comments on the website,... Read more
Posted on 01 March 2018 COMMUNITY, HEALTH -
Starting CAR-T Therapy For My CLL (chronic Lymphocytic Leukemia)
Friends and CLL Society supporters: This isn't easy. After consulting with my wife, my family, my closest friends and key supporters of the CLL Society, I... Read more
Posted on 24 February 2018 COMMUNITY, HEALTH -
Dr. Furman on The Diminishing Role of FCR in CLL (chronic Lymphocytic Leukemia)
As we're getting ready to head to ASH this week, we wanted to post in response to a query that was posted originally on the CLLSLL io group forum. Dr. Read more
Posted on 07 December 2017 COMMUNITY, HEALTH -
Giving Tuesday: Please Help the CLL Society Fulfill Its Mission of Helping...
Help the non profit CLL Society on Giving Tuesday at https://cllsociety.org/donate-to-cll-society/.At a recent CLL Society Patient Educational Forum, patients... Read more
Posted on 29 November 2017 COMMUNITY, HEALTH
