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A family member recently asked me, What's the connection between allergic reactions to wine and histamine levels in wine? She, like many people, abstains from drinking wine because it has resulted in adverse effects in the past. The answer to the question is both simple and complicated: If you are allergic to histamine, then you should avoid drinking some wines, because some wines contain higher amounts of histamine. Before I go into detail, let's get to the good news: Not all wines contain high levels of histamine. This means that some wines are ok to drink, even if you are allergic to histamine.
The reason that the histamine in wine is such a tricky, abstract concept is that it is very hard to accurately measure, unless you have a R-Biopharm kit or Microplate Strip Washer. Yeah, we're talking about photons and neutrons here folks. To give you an unhelpful definition used by biologists: Histamine is an endogenous compound that reacts poorly with H1 and H2 receptors.
