I'm a little busy with blog-syn and actual work at the moment, but a friend just sent me this screenshot from the Aldrich website, which I think I'll share with you all (annotation his):
Now, correct me if I'm wrong, but if I wanted to report a compound in, say, J. Med. Chem., I'm quite sure that TLC would not be an acceptable proof of purity. And if anyone knows how I can TLC quantitatively, please leave a comment, because I'm getting sick of running all these crude NMRs and HPLCs...