0 - Tis, N0, M0
Limited to mucosa
>95%
Local excision/polypectomy → Surveillance
No
No
II - T3-4, N0, M0
B
B reached bowel wall (muscularis propria)
70%
Wide surgical resection + Anastomosis
Adjuvant if: lymph node sampling <12, poorly differentiated, local invasion, occlusion/perforation, pT4)
FOLFOX or CapeOX
Yes, for rectal cancer (give with 5-FU as sensitizer)
IV - any T, any N, M1
D
D istant metastasis
10%
Surgical resection for - obstruction, some patients with hepatic, lung and peritoneal metastases
FOLFOX or FOLFIRI + Biologics
As above
+ Bone and Brain metastases
