Mnemonic: 10 S
- Sugar (diabetes) - most commonly foot and ankle
- Syringomyelia - 80% in shoulder and elbow
- Spinal cord injury - hip, knee, ankle and spine
- Spastic paraplegia
- Syphilis - most commonly knee
- Spirits (alcohol)
- Subacute combined degeneration
- Steroids
- Scaly disease (leprosy) - 2nd most common cause in upper extremity
- Scleroderma
3 Theories of Charcot Arthropathy
a. Neuro-traumatic: Damage to sensory feedback → Repeated microtrauma → Release of proinflammatory cytokines → Bone resorption
b. Neuro-vascular: Change in vascularity caused by dysregulation of vasomotor and trophic nerve supply
c. Neuro-inflammatory: Abnormal persistence of inflammatory response and inability to terminate inflammatory response
Classic features
Mnemonic: 6 Ds
- Destruction
- Disorganization
- Debris (loose bodies)
- Density (sclerosis)
- Distension (joint effusion)
- Dislocation (dislocation/subluxation)
Eichenholz classification
Mnemonic: CDCR or IFCC
- Clinical (Inflammatory) - Demineralization
- Dissolution (Fragmentation) - Debris and Dislocation
- Coalescence - Debris absorption and Density increase
- Resolution (Consolidation) - Deformity
Mnemonic: ABCDEF
- Activity limitation
- Bracing or Casting (Total contact cast)
- Discontinue when skin temperature normal
- Evade total joint arthroplasty
- Fusion after inflammatory phase in feet
0 - Clinical
Limited weight bearing (possibly TCC or PPWB), close observation
1 - Fragmentation
TCC, limited weight bearing
2 - Coalescence
TCC followed by CROW
3 - Reparative
Possible surgical intervention for removal of bony prominences associated with ulceration
