Electron microscopes can produce incredibly detailed or three dimensional views of sub-cellular structures, but often at the cost of losing the bigger picture. Researchers at Leiden University in the Netherlands, however, have leveraged a technique called virtual nanoscopy that enables researchers to observe the whole of a cell and its intricate details in a single image. With the method, the team stitches together nanometer resolution photographs of what’s gone under the scope to create a map with adjustable zoom a la Google Maps. Their study created a 281-gigapixel image (packed with 16 million pixels per inch) of a 1.5-millimeter-long zebrafish embryo.
Just as users of Google Earth can zoom in from space to a view of their own backyard, researchers can now navigate biological tissues from a whole embryo down to its subcellular structures thanks to recent advances in electron microscopy and image processing. Cool, huh?
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