In a game against the Chicago White Stockings on April 28, 1901, Cleveland Blues pitcher Bock Baker gave up 23 singles, which allowed Chicago to cruise to a 13-1 victory over the Blues. As a result, Baker was tagged with the dubious record for giving up the most singles by an American League pitcher in a game, a record that still stands to this day.
Cleveland Blues, 1901 logo (sportslogos.net)