In India and Middle East, it was traditionally used to treat indigestion, loss of appetite, fever, diarrhoea, general weakness, chest congestion, asthma and arthritis.
Therapeutic Activity
Nigella sativa seems to attribute its therapeutic activity to thymoquinone, the major active constituent of the volatile oil but the whole plant demonstrates:
- Anti-inflammatory
- Analgesic
- Antipyretic
- Antimicrobial
- Decreases triglycerides
- Hypocholesterolemic
- Hypoglycaemic
- Antioxidant
- Digestive
- Anthelmintic
- Carminative
- Diuretic
- Emmenagogue
- Galactagogue
- Chemoprevantative and antitumour activity (Antineoplastic)
- Protection against nephrotoxicity and hepatotoxicity induced by either disease or chemicals
Clinical trials
According to clinical trials, Black cumin improved the symptoms of allergic rhinitis, reduced hyperlipidaemia (high lipid blood levels) and has shown beneficial results with type 2 diabetes. However, more clinical trials are needed to confirm findings.
Other medicinal uses
- reduction of central obesity (3 g/day, taken for 3 months)
- Type 2 diabetes (2 g/day dose)
- fasting blood glucose decreased significantly
- HbA1c decreased by 1.5% at the end of the 12 weeks (p < 0.0001
- insulin resistance was reduced (p < 0.01) and beta-cell function was increased (p < 0.02) at 12 weeks
- H. pylori infection (2 g/day)
- Worm infestation
Caution
- Not to be used during pregnancy