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The two comic frames, above, were originally published in October of 1930, part of a two week story line. And yes, that's a gun in the second frame. Mickey Mouse, Walt Disney's iconic creation, is distraught, and looks to take his own life -- a huge departure from the Mouse we know today.
It's supposed to be comedy.
Mickey's suicidal saga spanned a few days -- four of them can be seen here. The plot: On the first day, Mickey catches Minnie cheating on him and, as seen above, decides to take his own life. For the next three days, he tries three different methods -- shooting himself using a Rube Goldberg-esque setup to fire the rifle; jumping off a bridge; and poisoning himself with gas from his radiator (below) -- and all three times, Mickey fails in what is intended to be a comical fashion. The rifle shot is interrupted by a cuckoo clock, with Mickey realizing that he'd be cuckoo to try and shoot himself. Mickey's dive off the bridge lands him on a boat, where he becomes a de facto stowaway; the captain threatens to throw him overboard, and Mickey ironically begs him not to, as he can't swim and will certainly drown. And Mickey's asphyxiation fails when a squirrel-like character tries to fill a balloon with the gas, waking Mickey (who thinks he has just been shot). The humor is likely lost on modern audiences, but apparently, the depravity did not seem to concern audiences contemporary with the strips' publication.