This trial in previously treated CLL patients showed a clinically significant progression free survival when compared to a combination regimen of rituximab plus physician’s choice of idelalisib or bendamustine. No new side effects or problems were noted.While not unexpected, it is important to have this trial confirmation that another BTK inhibitor, like ibrutinib has proven to save lives.This is more good news for CLL patients. Acalabrutinib is already approved for mantle cell lymphoma (MCL) and hopefully will be soon approved for us CLL patients based on this and Phase 3 trials that should have positive results soon.While not approved for CLL, because it is approved for MCL and is part of the NCCN guidelines for CLL, it is already an option today for appropriate CLL patients if your doctor pushes for it.Here is a link to a nice review of the data we have so far and more trial news.Here is the official press release.It is good to have more choices of all these great drugs. Can’t wait for approval to make it easier to access.Stay strong,BrianBrian Koffman MDCM DCFP, DABFM, MS Ed
Co-Founder, Executive VP and Chief Medical Officer
CLL Society, Inc.
If you want a personal response, or just want to stay in touch, please email me at bkoffmanMD@gmail.com. I have no other way of contacting. Thanks. Stay strong. After all, we are all in this together. And please visit our website: http://cllsociety.org for the latest news and information.
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