Having played in 2,130 consecutive games, Lou Gehrig’s streak–and career–came to an end on April 30, 1939. Gehrig went 0-for-4 in his final appearance against the Senators. His performance had been declining for some time, and Gehrig would later be diagnosed by the Mayo Clinic with amyotrophic lateral sclerosis (ALS), now more commonly known as Lou Gehrig’s disease. During his seventeen-year career with the Yankees, Gehrig compiled a .340 batting average and 493 home runs.
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